Gastrointestinal tuberculosis accounts for 1% to 3 % of all TB cases worldwide. Colonic tuberculosis is rare and can be mistaken for malignancy. It commonly presents as chronic abdominal pain along with night sweats, diarrhea, and fatigue and can resemble variety of other diseases making the diagnosis difficult. It presents with vague clinical and radiological picture making the diagnosis challenging for the clinicians. Its diagnosis is usually made by combining clinical features, radiological, tissue AFP staining and histopathologal examinations. The typical histopathologic findings include confluent large granulomas and langhans giant cells with caseating necrosis. Gastrointestinal tuberculosis responds well to standard antituberculous drugs and surgery is done for patients that have complications like strictures or obstruction which does not respond to medical therapy. This case illustrates a 40 year old man who presented with crampy lower abdominal pain and diagnosed as a colonic cancer both on imaging and clinically which later found to have colonic tuberculosis on a colectomy histopathologic sample. He was treated with anti-TB and respond well to his treatment. This case will give an insight for treating physicians to have a high index of suspicion for colonic TB in a patient who presented with lower abdominal pain and having colonic mass.
Published in | American Journal of Laboratory Medicine (Volume 9, Issue 4) |
DOI | 10.11648/j.ajlm.20240904.11 |
Page(s) | 41-44 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Colon, Tuberculosis, Carcinoma
[1] | Sheer TA, Coyle WJ. Gastrointestinal tuberculosis. Curr Gastroenterol Rep. 2003 Aug; 5(4): 273-8. |
[2] | Chakinala RC, Khatri AM. Gastrointestinal Tuberculosis. Stat Pearls. Treasure Island (FL): StatPearls Publishing, 2021. |
[3] | Uma Debi, Vasudevan Ravisankar, Kaushal Kishor Prasad, Saroj Kant Sinha, Arun Kumar Sharma World journal of gastroenterology, Abdominal tuberculosis of gastrointestinal tract: 2014, 14832-14839. |
[4] | Alvares JF, Devarbhavi H, Makhija P, Rao S, Kottoor R: Clinical, colonoscopic, and histological profile of colonic tuberculosis in a tertiary hospital. Endoscopy; 2005; 37(4): 351–6. |
[5] | Elroy Patrick Weledji and Benjamin Thumamo Pokam, Abdominal tuberculosis: Is there a role for surgery? World journal of gastroenterology 2017; 174-181. |
[6] | American Thoracic Society C, Infectious Diseases Society of America Treatment of tuberculosis. 2003; 52: 1–77. |
[7] | Lau CF, et al. A case of colonic tuberculosis mimicking Crohn's disease. Hong Kong Medical Journal 4(1998): 63-66. |
[8] | Yun Jung Lee, Suk-Kyun Yang, Seung Jae Myung, “The usefulness of colonoscopic biopsy in the diagnosis of intestinal tuberculosis and pattern of concomitant extra-intestinal tuberculosis” The Korean journal of gastroenterology, vol. 44, no. 3, pp. 153-159, 2004. |
[9] | Lowbridge, C., Fadhil, S. A. M., Krishnan, G. D. et al. How can gastro-intestinal tuberculosis diagnosis be improved? A prospective cohort study. BMC Infect Dis 20, 255(2020). |
[10] | R. S. Wiener, P. Della-Latta, and N. W. Schluger, “Effect of nucleic acid amplification for Mycobacterium tuberculosis on clinical decision making in suspected extrapulmonary tuberculosis,” Chest, vol. 128, no. 1, pp. 102–107, 2005. |
[11] | Dong Ho Lee, MD, Young Tae Ko, MD, Yup Yoon, MD, Jae Hoon Lim, MD: Sonographic Findings of Intestinal Tuberculosis: 537-540. |
[12] | S. Mukewar, R. Ravi, and A. Prasad, “Colon tuberculosis: endoscopic features and prospective endoscopic follow-up after anti-tuberculosis treatment,” Clinical and Translational Gastroenterology, vol. 3, 24 pages, 2012. |
[13] | P. B. Tripathi and A. D. Amarapurkar, “Morphological spectrum of gastrointestinal tuberculosis, Trop Gastroenterology”, Vol, 30, no. 1, pp. 35-39, 2009. |
APA Style
Lucas, F. Y., Tadele, A. K., Engida, G. G., Geremew, T. T., Wodajo, A. A., et al. (2024). Colonic Tuberculosis Mimicking Colonic Cancer: A Multidisciplinary Diagnosis and Case Report. American Journal of Laboratory Medicine, 9(4), 41-44. https://doi.org/10.11648/j.ajlm.20240904.11
ACS Style
Lucas, F. Y.; Tadele, A. K.; Engida, G. G.; Geremew, T. T.; Wodajo, A. A., et al. Colonic Tuberculosis Mimicking Colonic Cancer: A Multidisciplinary Diagnosis and Case Report. Am. J. Lab. Med. 2024, 9(4), 41-44. doi: 10.11648/j.ajlm.20240904.11
@article{10.11648/j.ajlm.20240904.11, author = {Fekade Yerakley Lucas and Abraham Kassahun Tadele and Ghion Getnet Engida and Teketel Tadesse Geremew and Abebaw Amare Wodajo and Melaku Teshale Gemechu and Menberu Moges Ayele and Kalkidan Molla Tegengne and Akmel Umer Ebrahim and Tigist Gutema Tesgera}, title = {Colonic Tuberculosis Mimicking Colonic Cancer: A Multidisciplinary Diagnosis and Case Report }, journal = {American Journal of Laboratory Medicine}, volume = {9}, number = {4}, pages = {41-44}, doi = {10.11648/j.ajlm.20240904.11}, url = {https://doi.org/10.11648/j.ajlm.20240904.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20240904.11}, abstract = {Gastrointestinal tuberculosis accounts for 1% to 3 % of all TB cases worldwide. Colonic tuberculosis is rare and can be mistaken for malignancy. It commonly presents as chronic abdominal pain along with night sweats, diarrhea, and fatigue and can resemble variety of other diseases making the diagnosis difficult. It presents with vague clinical and radiological picture making the diagnosis challenging for the clinicians. Its diagnosis is usually made by combining clinical features, radiological, tissue AFP staining and histopathologal examinations. The typical histopathologic findings include confluent large granulomas and langhans giant cells with caseating necrosis. Gastrointestinal tuberculosis responds well to standard antituberculous drugs and surgery is done for patients that have complications like strictures or obstruction which does not respond to medical therapy. This case illustrates a 40 year old man who presented with crampy lower abdominal pain and diagnosed as a colonic cancer both on imaging and clinically which later found to have colonic tuberculosis on a colectomy histopathologic sample. He was treated with anti-TB and respond well to his treatment. This case will give an insight for treating physicians to have a high index of suspicion for colonic TB in a patient who presented with lower abdominal pain and having colonic mass. }, year = {2024} }
TY - JOUR T1 - Colonic Tuberculosis Mimicking Colonic Cancer: A Multidisciplinary Diagnosis and Case Report AU - Fekade Yerakley Lucas AU - Abraham Kassahun Tadele AU - Ghion Getnet Engida AU - Teketel Tadesse Geremew AU - Abebaw Amare Wodajo AU - Melaku Teshale Gemechu AU - Menberu Moges Ayele AU - Kalkidan Molla Tegengne AU - Akmel Umer Ebrahim AU - Tigist Gutema Tesgera Y1 - 2024/09/29 PY - 2024 N1 - https://doi.org/10.11648/j.ajlm.20240904.11 DO - 10.11648/j.ajlm.20240904.11 T2 - American Journal of Laboratory Medicine JF - American Journal of Laboratory Medicine JO - American Journal of Laboratory Medicine SP - 41 EP - 44 PB - Science Publishing Group SN - 2575-386X UR - https://doi.org/10.11648/j.ajlm.20240904.11 AB - Gastrointestinal tuberculosis accounts for 1% to 3 % of all TB cases worldwide. Colonic tuberculosis is rare and can be mistaken for malignancy. It commonly presents as chronic abdominal pain along with night sweats, diarrhea, and fatigue and can resemble variety of other diseases making the diagnosis difficult. It presents with vague clinical and radiological picture making the diagnosis challenging for the clinicians. Its diagnosis is usually made by combining clinical features, radiological, tissue AFP staining and histopathologal examinations. The typical histopathologic findings include confluent large granulomas and langhans giant cells with caseating necrosis. Gastrointestinal tuberculosis responds well to standard antituberculous drugs and surgery is done for patients that have complications like strictures or obstruction which does not respond to medical therapy. This case illustrates a 40 year old man who presented with crampy lower abdominal pain and diagnosed as a colonic cancer both on imaging and clinically which later found to have colonic tuberculosis on a colectomy histopathologic sample. He was treated with anti-TB and respond well to his treatment. This case will give an insight for treating physicians to have a high index of suspicion for colonic TB in a patient who presented with lower abdominal pain and having colonic mass. VL - 9 IS - 4 ER -